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Internal calibration routine for one-stage single-arm BF designs

Usage

optimal_onestage_singlearm_bf(
  n_min,
  n_max,
  k,
  p0,
  a0 = 1,
  b0 = 1,
  a1 = 1,
  b1 = 1,
  dp = NA_real_,
  da0 = 1,
  db0 = 1,
  da1 = 1,
  db1 = 1,
  type = c("point", "direction"),
  calibration = c("Bayesian", "frequentist", "hybrid", "full"),
  target_power = 0.8,
  target_type1 = 0.05,
  target_ce_h0 = 0,
  target_freq_power = 0.8,
  target_freq_type1 = 0.05,
  power_cushion = 0,
  k_ce = NULL,
  sustain_n = 10L
)

Arguments

n_min

Integer. Minimum admissible sample size in the search grid.

n_max

Integer. Maximum admissible sample size in the search grid.

k

Numeric scalar greater than 0. Evidence threshold on the \(BF_{01}\) scale used for efficacy.

p0

Numeric scalar in \((0,1)\). Null response probability.

a0, b0

Positive numeric scalars. Beta analysis-prior parameters under \(H_0\).

a1, b1

Positive numeric scalars. Beta analysis-prior parameters under \(H_1\).

dp

Optional numeric scalar in \((0,1)\). Fixed point alternative used for frequentist power calculations under \(H_1\).

da0, db0

Positive numeric scalars. Beta design-prior parameters under \(H_0\).

da1, db1

Positive numeric scalars. Beta design-prior parameters under \(H_1\).

type

Character string specifying the Bayes-factor test. One of "point" or "direction".

calibration

Character string specifying the calibration mode. One of "Bayesian", "frequentist", "hybrid", or "full".

target_power

Numeric scalar in \((0,1)\). Target corrected Bayesian power.

target_type1

Numeric scalar in \((0,1)\). Target corrected Bayesian type-I error.

target_ce_h0

Numeric scalar in \([0,1)\). Optional lower bound on the corrected Bayesian probability of compelling evidence in favour of \(H_0\).

target_freq_power

Numeric scalar in \((0,1)\). Target corrected frequentist power at dp.

target_freq_type1

Numeric scalar in \((0,1)\). Target corrected frequentist type-I error at \(p = p_0\).

power_cushion

Non-negative numeric scalar. Optional additive cushion applied to the power targets during calibration.

k_ce

Optional numeric scalar greater than 1. Threshold on the \(BF_{01}\) scale used for CE(H0) / PCE(H0) calculations.

sustain_n

Non-negative integer. A candidate sample size is declared feasible only if the relevant constraints are satisfied at that sample size and for the next sustain_n larger sample sizes, subject to the search range.

Value

A list with feasibility, selected design, operating characteristics, and full search results.